Brisbane, Queensland, Australia--(ACN Newswire via SeaPRwire.com - April 22, 2026) - Graphene Manufacturing Group Ltd (TSXV: GMG) (OTCQX: GMGMF) ("GMG" or the "Company") is pleased to announce that Stuart Watson — former global Head of Technical Development for Rio Tinto Ltd. (ASX: RIO), one of the largest mining and mineral production companies in the world, has joined GMG as Chief Production Growth Officer.Stuart has over 30 years of global leadership experience in metals and mining and oil and chemicals, including 20 years at Rio Tinto, across operations, sales and marketing, mergers and acquisitions, and technology development and innovation. Career highlights include:Leading and delivering multiple major transformation programs valued over US$5 Billion and merger and acquisition deals valued at US$1 Billion.Directing US$1 Billion in global technology and research & development spend to create breakthrough growth options and projectsBuilding high-performing global teams across Asia, Europe, and North AmericaStuart has a Master of Business Administration (MBA) - Henley Management College, UK; is a Chartered Engineer - Institute of Chemical Engineers (IChemE), has a Masters of Engineering, Chemical Engineering (First Class Honours) — Imperial College, University of London and Ecole Nationale Supérieure d'Ingénieurs de Génie Chimique (ENSIGC), Toulouse, France.Craig Nicol, CEO & Managing Director of the Company, commented "We welcome Stuart to the GMG team - he is a great addition to the Senior Executive Team for both executive leadership and delivery capability. I will enjoy working with Stuart to expand our production across our graphene and graphene products around the world."Jack Perkowski, Non-Executive Chairman and Director of the Company, commented: "On behalf of the board I welcome Stuart to the team and look forward to the progress around expanding our production capability into North America."Operations UpdateGMG is focused on delivering its Gen 2.0 Graphene Production Project (the "Gen 2.0 Project") by end of June 2026 — which is expected to produce at least 10 tonnes per annum of graphene at its headquarters in Richlands, Queensland, Australia.Once the Gen 2.0 Project is commissioned and operating. GMG plans to replicate and establish other production plants around the world to enable scaled production for potential sales, diversify and lower production risks, and in the end, reduce operating costs by locating the plant in countries with lower operating costs, including low cost natural gas — one of GMG's key production input costs.Currently, GMG is planning three potential expansion projects — two in North America (potentially one in US and one in Canada) in addition to an expansion production project in Australia. GMG proposes to mature these projects and expand production in line with sales for all of its products.The expansion program for GMG includes the following 5 production plants:Graphene Production (from natural gas)Coating Blend Plant (for the graphene coating THERMAL-XR®)Lubricant Blend Plant (for the graphene lubricant additive G® LUBRICANT)Graphene Slurry Plant (for the SUPA G Lithium-Ion Battery Additive)Battery Assembly Plant (for the Graphene Aluminium Ion Battery)Figure 1To view an enhanced version of this graphic, please visit:https://images.newsfilecorp.com/files/8082/293781_d1c07d1d84356a2d_001full.jpgAbout GMG:GMG is an Australian based clean-technology company which develops, makes and sells energy saving and energy storage solutions, enabled by graphene manufactured via in house production process. GMG uses its own proprietary production process to decompose natural gas (i.e. methane) into its natural elements, carbon (as graphene), hydrogen and some residual hydrocarbon gases. This process produces high quality, low cost, scalable, 'tuneable' and low/no contaminant graphene suitable for use in clean-technology and other applications.The Company's present focus is to de-risk and develop commercial scale-up capabilities, and secure market applications. In the energy savings segment, GMG has initially focused on graphene enhanced heating, ventilation and air conditioning ("HVAC-R") coating (or energy-saving coating) which is now being marketed into other applications including electronic heat sinks, industrial process plants and data centres. Another product GMG has developed is the graphene lubricant additive focused on saving liquid fuels initially for diesel engines.In the energy storage segment, GMG and the University of Queensland are working collaboratively with financial support from the Australian Government to progress R&D and commercialization of graphene aluminium-ion batteries ("G+AI Batteries"). GMG has also developed a graphene additive slurry that is aimed at improving the performance of lithium-ion batteries.GMG's 4 critical business objectives are:Produce Graphene and improve/scale cell production processesBuild Revenue from Energy Savings ProductsDevelop Next-Generation BatteryDevelop Supply Chain, Partners & Project Execution CapabilityFor further information please contact:Craig Nicol, Chief Executive Officer & Managing Director of the Company at craig.nicol@graphenemg.com, +61 415 445 223Leo Karabelas at Focus Communications Investor Relations, leo@fcir.ca, +1 647 689 6041Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accept responsibility for the adequacy or accuracy of this news release.Cautionary Note Regarding Forward-Looking StatementsThis news release includes certain statements and information that may constitute forward-looking information within the meaning of applicable Canadian and U.S. securities laws. Forward-looking statements relate to future events or future performance and reflect the expectations or beliefs of management of the Company regarding future events. Generally, forward-looking statements and information can be identified by the use of forward-looking terminology such as "intends", "believes" "expects" or "anticipates", or variations of such words and phrases or statements that certain actions, events or results "may", "could", "should", "would" or will "potentially" or "likely" occur. This information and these statements, referred to herein as "forward‐looking statements", are not historical facts, are made as of the date of this news release and include without limitation, statements as to GMG's focus on, and the timing and production expectations of, the Gen 2 Project, intentions regarding the number, purpose and location of expansion projects, intentions to de-risk and develop commercial scale-up capabilities, GMG's focus in the energy savings segment, GMG's intentions for the use of graphene lubricant additive on saving liquid fuels, expectations for R&D and commercialization of G+AI Batteries, GMG's ability to improve the performance of lithium-ion batteries and GMG's critical business objectives.Such forward-looking statements are based on a number of assumptions of management, including the patent and potential market size of G® LUBRICANT. Additionally, forward-looking information involves a variety of known and unknown risks, uncertainties and other factors which may cause the actual plans, intentions, activities, results, performance or achievements of GMG to be materially different from any future plans, intentions, activities, results, performance or achievements expressed or implied by such forward-looking statements. Such risks include, without limitation that GMG does not receive or receive on a timely basis the fully signed consent notice from the and the risk factors set out under the heading "Risk Factors" in the Company's annual information form dated November 4, 2025 available for review on the Company's profile at www.sedarplus.ca.Although management of the Company has attempted to identify important factors that could cause actual results to differ materially from those contained in forward-looking statements or forward-looking information, there may be other factors that cause results not to be as anticipated, estimated or intended. There can be no assurance that such statements will prove to be accurate, as actual results and future events could differ materially from those anticipated in such statements. Accordingly, readers should not place undue reliance on forward-looking statements and forward-looking information. Readers are cautioned that reliance on such information may not be appropriate for other purposes. The Company does not undertake to update any forward-looking statement, forward-looking information or financial out-look that are incorporated by reference herein, except in accordance with applicable securities laws.To view the source version of this press release, please visit https://www.newsfilecorp.com/release/293781 Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

Transaction will create a global powerhouse for mining finance and reduce complexity and costs for Canadian market participantsAcquisition will strengthen TMX's ability to serve clients across the capital markets ecosystem, expands global presence, accelerates growth strategyAnalyst webcast and conference call on Wednesday, April 22, 2026 at 8:00am EDT to discussToronto, Ontario--(ACN Newswire via SeaPRwire.com - April 22, 2026) - TMX Group Limited (TSX: X) (TMX Group) announced today an agreement to acquire Middlebury Holdings Pty. Limited (Cboe Australia) and Cboe Canada Holdings, ULC (Cboe Canada) from Cboe Global Markets, Inc. for US$300 million ($409 million*) in total consideration, a transaction that will bolster TMX's ability to serve clients across the capital markets ecosystem, expand the company's global presence, and accelerate the company's growth strategy, while reducing cost and complexity for Canadian market participants."We are tremendously excited to announce the acquisition of Cboe Australia and Cboe Canada, a deal that represents a unique opportunity to strengthen our domestic marketplace for clients and the entire stakeholder ecosystem, while expanding the reach and impact of our presence in a region of the world we know well," said John McKenzie, Chief Executive Officer, TMX Group. "We look forward to working with our industry partners to ensure a smooth transition, and to exploring innovative ways to serve the needs of issuers and investors across the Australian market, while continuing to seek out opportunities to accelerate our enterprise growth strategy."Cboe Australia and Cboe Canada offer equities trading venues, listing venues and market data solutions. Cboe Australia is an innovative securities exchange offering companies strategic tailored support for public market listings, including ETFs, as well as structured products and warrants, and providing a trading venue for brokers and investors with efficient and cost-effective access to local and global investment opportunities. Cboe Australia was also recently granted a license for corporate listings. Cboe Canada includes MATCHNow, NEO-L, NEO-N, and NEO-D, as well as ETF, CDR and corporate listings."The teams at Cboe Australia and Cboe Canada have delivered consistent performance and built resilient, high-quality markets," said Craig Donohue, Chief Executive Officer, Cboe Global Markets. "These businesses are well positioned for their next chapter, and we will work closely with TMX, our local regulators, and our clients to ensure a seamless transition."Transaction HighlightsTMX's acquisition of Cboe Australia will bring together the world's leading mining and energy transition financing ecosystems, unlocking potential to innovate for a growing global client base.TMX's acquisition of Cboe Canada enhances the quality of client experience across domestic equities marketplaces:Increasing efficiency of access to capital and liquidity for Canadian issuers, andReducing direct and indirect costs for participants, while improving execution quality and resiliency.Transaction expected to be accretive to adjusted earnings per share within the first 12 months of closing, excluding synergies.Revenue growth expected to be in-line with TMX's long-term financial objectivesCombined Cboe Canada and Cboe Australia businesses delivered revenue of approximately $87 million in 2025, and adjusted EBITDA of approximately $25 million**.Further Transaction DetailsThe purchase of each business is subject to regulatory approvals and customary closing conditions in Australia and Canada. The two components of this acquisition, Cboe Australia and Cboe Canada, are expected to close separately, each after required approvals have been obtained.Canaccord Genuity and Macquarie Capital are acting as financial advisors to TMX Group. FGS Longview is acting as strategic communications advisor to TMX Group.*Based on USD/CAD exchange rate of 1.3644 at April 21, 2026. Actual amounts in Canadian dollars are subject to change.**Based on average AUD/CAD of 0.90 for 2025. Cboe Australia and Canada revenue and EBITDA are compilations of financial information provided to us for the Cboe entities as of December 31, 2025. The Cboe financial information is unaudited and prepared in accordance with IFRS (Cboe Canada) or Australian Accounting Standards (Cboe Australia) for public companies.Teleconference / Audio WebcastTMX Group will host a teleconference / audio webcast to discuss the transaction.Time: 8:00 a.m. - 9:00 a.m. ET on Wednesday, April 22, 2026Participants may access the conference call via the webcast link: https://www.gowebcasting.com/14669.The audio webcast of the conference call and investor presentation will also be available on TMX Group's website at www.tmx.com, under Investor Relations.Alternatively, participants may join the live call by dialing 1-833-752-4317 or 1-647-846-2266.An audio replay of the conference call will be available at 1-855-669-9658 or 1-412-317-0088, [access code 6830744].Caution Regarding Forward-Looking InformationThis press release of TMX Group Limited ("TMX Group", "us", "we", "our") contains "forward-looking information" (as defined in applicable Canadian securities legislation) that is based on expectations, assumptions, estimates, projections and other factors that management believes to be relevant as of the date of this press release. Often, but not always, such forward-looking information can be identified by the use of forward-looking words such as "plans", "expects", "projects", "is expected", "projected", "budget", "scheduled", "targeted", "estimates", "forecasts", "intends", "anticipates", "believes", or variations or the negatives of such words and phrases or statements that certain actions, events or results "may", "could", "would", "might" or "will" be taken, occur or be achieved or not be taken, occur or be achieved. Forward-looking information, by its nature, requires TMX Group to make assumptions and is subject to significant risks and uncertainties which may give rise to the possibility that our expectations or conclusions will not prove to be accurate and that our assumptions may not be correct. Examples of forward-looking information in this press release include, but are not limited to, the anticipated benefits of the transactions to TMX Group, Cboe Canada and Cboe Australia; the expected impact on TMX Group's earnings and Adjusted earnings per share; expectations regarding the revenue growth of Cboe Canada and Cboe Australia; the ability to integrate Cboe Canada and Cboe Australia into TMX Group and the potential synergies; the expected impact on TMX's long-term growth strategy and transformational objectives; the potential for geographic expansion; the ability for TMX Group to accelerate Cboe Canada and Cboe Australia's growth; the timing and receipt of regulatory approval; and closing of the transaction, each of which is subject to a number of significant risks and uncertainties. These risks include, but are not limited to: competition from other exchanges or marketplaces, including alternative trading systems and new technologies, on a national and international basis; dependence on the economies of Canada, the United States and Australia; adverse effects on our results caused by global economic conditions (including geopolitical events, interest rate movements or threats of recession) or uncertainties including changes in business cycles that impact our sector; failure to retain and attract qualified personnel; geopolitical and other factors which could cause business interruption; dependence on information technology; vulnerability of our networks and third party service providers to security risks, including cyber attacks; failure to properly identify or implement our strategies; regulatory constraints; constraints imposed by our level of indebtedness, risks of litigation or other proceedings; dependence on adequate numbers of customers; failure to develop, market or gain acceptance of new products; failure to close and effectively integrate acquisitions, including the Cboe Canada and Cboe Australia acquisition, to achieve planned economics or divest underperforming businesses; currency risk; adverse effect of new business activities; adverse effects from business divestitures; not being able to meet cash requirements because of our holding company structure and restrictions on paying inter-corporate dividends; dependence on third party suppliers and service providers; dependence of trading operations on a small number of clients; risks associated with our clearing operations; challenges related to international expansion; restrictions on ownership of TMX Group common shares; inability to protect our intellectual property; adverse effect of a systemic market event on certain of our businesses; risks associated with the credit of customers; cost structures being largely fixed; the failure to realize cost reductions in the amount or the time frame anticipated; dependence on market activity that cannot be controlled; the regulatory constraints that apply to the business of TMX Group and its regulated subsidiaries, costs of on exchange clearing and depository services, trading volumes (which could be higher or lower than estimated) and the resulting impact on revenues; future levels of revenues being lower than expected or costs being higher than expected.Forward-looking information is based on a number of assumptions which may prove to be incorrect, including, but not limited to, assumptions with respect to the impact of the cost of acquisition financing on adjusted earnings per share; assumptions in connection with the ability of TMX Group to successfully compete against global and regional marketplaces and other venues; business and economic conditions generally; exchange rates (including estimates of exchange rates from Canadian dollars to the U.S. dollar, British pound sterling, or Australian dollar), commodities prices, the level of trading and activity on markets, and particularly the level of trading in TMX Group's key products; business development and marketing and sales activity; the continued availability of financing on appropriate terms for future projects; changes to interest rates and the timing thereof; productivity at TMX Group, as well as that of TMX Group's competitors; market competition; research and development activities; the successful introduction and client acceptance of new products and services; successful introduction of various technology assets and capabilities; the impact on TMX Group and its customers of various regulations; TMX Group's ongoing relations with its employees; and the extent of any labour, equipment or other disruptions at any of its operations of any significance other than any planned maintenance or similar shutdowns.In addition to the assumptions outlined above, forward looking information related to long term revenue CAGR objectives, and long term adjusted earnings per share CAGR objectives are based on assumptions that include, but not limited to:TMX Group's success in achieving growth initiatives and business objectives;continued investment in growth businesses and in transformation initiatives including next generation technology and systems;no significant changes to our effective tax rate, and number of shares outstanding;organic and inorganic growth in recurring revenuemoderate levels of market volatility over the long term;level of listings, trading, and clearing consistent with historical activity;economic growth consistent with historical activity;no significant changes in regulations;continued disciplined expense management across our business;continued re-prioritization of investment towards enterprise solutions and new capabilities;free cash flow generation consistent with historical run rate; anda limited impact from inflation, rising interest rates and supply chain constraints on our plans to grow our business over the long term including on the ability of our listed issuers to raise capital.While we anticipate that subsequent events and developments may cause TMX Group's views to change, TMX Group has no intention to update this forward-looking information, except as required by applicable securities law. This forward-looking information should not be relied upon as representing TMX Group's views as of any date subsequent to the date of this press release. TMX Group has attempted to identify important factors that could cause actual actions, events or results to differ materially from those current expectations described in forward-looking information. However, there may be other factors that cause actions, events or results not to be as anticipated, estimated or intended and that could cause actual actions, events or results to differ materially from current expectations. There can be no assurance that forward-looking information will prove to be accurate, as actual results and future events could differ materially from those anticipated in such statements. Accordingly, readers should not place undue reliance on forward-looking information. These factors are not intended to represent a complete list of the factors that could affect TMX Group. Important additional information identifying risks and uncertainties and other factors is contained in TMX Group's 2025 Annual Report under the headings entitled "Caution Regarding Forward-Looking Information" and "Enterprise Risk Management" which may be accessed at tmx.com in the Investor Relations section under Regulatory Filings.Non-GAAP Financial MeasuresThis press release includes references to financial measures that are not defined by GAAP. Although such non-GAAP measures are calculated according to accepted industry practice, such measures disclosed in this press release may be different from non-GAAP measures used by other companies. This data is intended to provide additional information and should not be considered in isolation or as a substitute for measures of performance prepared in accordance with GAAP. While TMX Group believes these measures provide investors with greater transparency and supplemental data relating to the transaction, readers are cautioned that these non-GAAP measures are not alternatives to measures determined in accordance with GAAP and should not, on their own, be construed as indicators of TMX Group's or Cboe Canada and Cboe Australia's future performance or profitability. Readers should not rely on any single financial measure when evaluating TMX Group's business or that of Cboe Canada and Cboe Australia. We use non-GAAP measures and non-GAAP ratios that do not have standardized meanings prescribed by GAAP and are, therefore, unlikely to be comparable to similar measures presented by other companies. Management uses these measures, and excludes certain items, because it believes doing so provides investors a more effective analysis of underlying operating and financial performance, including, in some cases, our ability to generate cash and our ability to repay debt. Management also uses these measures to more effectively measure performance over time, and excluding these items increases comparability across periods. The exclusion of certain items does not imply that they are non-recurring or not useful to investors.Adjusted earnings per share provided above is a non-GAAP ratio and does not have a standardized meaning prescribed by GAAP and is therefore unlikely to be comparable to similar measures presented by other companies. TMX Group presents Adjusted EPS and excludes, among other things, acquisition, integration, and related items; amortization of intangibles related to acquisitions; strategic re-alignment expenses; dispute, litigation and related items; and other items as disclosed in TMX Group's 2025 Annual Report. For more information on Adjusted EPS, including definitions and explanations of how these measures provide useful information, refer to Non-GAAP Measures in TMX Group's 2025 Annual Report.Adjusted EBITDA is calculated as net income excluding interest expense, income tax expense, depreciation and amortization, acquisition, integration, and related costs, one-time income (loss), and other significant items that are not reflective of the underlying business operations of Cboe Canada and Cboe Australia. Cboe Canada and Cboe Australia Adjusted EBITDA is a compilation of financial information provided to us for Cboe Canada and Cboe Australia entities as of December 31, 2025. The Cboe Canada and Cboe Australia financial information is unaudited and prepared in accordance with IFRS (Cboe Canada) or Australian Accounting Standards (Cboe Australia) for public companies. Adjusted EBITDA for Cboe Canada and Cboe Australia excludes certain items such as discontinued operations, transfer pricing, unrealized gains / losses, and one-time employee costs.About TMX Group (TSX: X) TMX Group operates global markets, and builds digital communities and analytic solutions that facilitate the funding, growth and success of businesses, traders and investors. TMX Group's key operations include Toronto Stock Exchange, TSX Venture Exchange, TSX Alpha Exchange, The Canadian Depository for Securities, Montréal Exchange, Canadian Derivatives Clearing Corporation, TSX Trust, TMX Trayport, TMX Datalinx, TMX VettaFi and TMX Newsfile, which provide listing markets, trading markets, clearing facilities, depository services, technology solutions, data products and other services to the global financial community. TMX Group is headquartered in Toronto and operates offices across North America (Montréal, Calgary, Vancouver and New York), as well as in key international markets including London, Singapore, and Vienna. For more information about TMX Group, visit www.tmx.com. Follow TMX Group on X: @TMXGroup.For more information please contact:Catherine KeeHead of Media RelationsTMX Group416-671-1704catherine.kee@tmx.comAmanda TangHead of Investor RelationsTMX Group416-895-5848amanda.tang@tmx.com To view the source version of this press release, please visit https://www.newsfilecorp.com/release/293729 Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

HONG KONG, Apr 22, 2026 - (ACN Newswire via SeaPRwire.com) - Hengrui Pharma reported steady growth in the first quarter of 2026. In Q1 2026, the Company recorded revenue of RMB 8.14 billion, up 12.98% year-over-year, while net profit attributable to shareholders increased by 21.78% to RMB 2.28 billion. Innovative drugs remained the key growth driver, generating RMB 4.53 billion in revenue, up 25.75% year-over-year and accounting for 61.69% of total pharmaceutical sales.The Company continued to advance its innovation-driven strategy with sustained R&D investment and solid pipeline progress. R&D investments in Q1 2026 totaled RMB 2.22 billion, representing for approximately 27.32% of revenue.During the period, three innovative products and new indications were approved in China, which included an anti-PD-L1/TGF-βRII bi-functional fusion protein and an indication expansion for HER2-targeting ADC.In terms of pipeline advancement, the Company obtained 26 clinical trial approvals and had 8 new drug applications accepted in China across key therapeutic areas including oncology, metabolic, cardiovascular, and immunological diseases.Business development has become a recurring and increasingly important growth driver, with RMB 787 million in out-licensing revenue recognized during the quarter, primarily from the collaboration with GSK. Since 2023, Hengrui Pharma has completed 12 overseas business development transactions, including out-licensing, NewCo structures, and strategic alliance models.A key milestone during the period was the successful Nasdaq listing of Kailera Therapeutics (NASDAQ: KLRA), a NewCo company built around Hengrui Pharma’s GLP-1-based assets. This milestone reflects continued progress in executing the Company’s NewCo strategy, with Hengrui and Kailera working together to advance the global development of the GLP-1 portfolio.Looking ahead, Hengrui Pharma will remain committed to innovation and globalization, strengthening its pipeline and advancing the development and commercialization of innovative therapies to benefit patients worldwide. Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

HONG KONG, Apr 22, 2026 - (ACN Newswire via SeaPRwire.com) - Apr 20, Everest Medicines announced that the first-in-human (FIH) clinical trial data of EVM16, a proprietary personalized mRNA cancer vaccine, were presented at the 2026 American Association for Cancer Research Annual Meeting (AACR 2026). The data include results from EVM16 as a monotherapy and in combination with the PD-1 inhibitor tislelizumab in patients with advanced solid tumors. The results demonstrated that EVM16 has a favorable safety and tolerability profile, robust immunogenicity, and promising preliminary efficacy in patients with advanced solid tumors, supporting its further clinical development.The clinical trial (EVM16CX01, NCT06541639) was conducted jointly by Peking University Cancer Hospital and Fudan University Shanghai Cancer Center, with the first patient dosed in March 2025. EVM16CX01 is a first-in-human (FIH), dose-escalation, and expansion study evaluating the safety, tolerability, immunogenicity, and preliminary efficacy of EVM16 injection as a monotherapy and in combination with tislelizumab in patients with advanced solid tumors. The study follows a 3+3 dose-escalation design across three dose levels (0.1 mg, 0.3 mg, and 1.0 mg). Eligible patients are those with advanced or recurrent solid tumors who have failed standard of care and have at least one measurable target lesion. Patients receive 2 doses of EVM16 monotherapy once every two weeks, followed by combination therapy of EVM16 and tislelizumab. As of December 7, 2025, a total of 9 patients had been enrolled.No dose-limiting toxicities (DLTs) were observed. All patients experienced at least one investigational product (IP) related adverse event (AE), all of which were Grade ≤ 2 and resolved spontaneously. EVM16 elicited strong neoantigen-specific T cell responses in 8 of 9 patients, which showed a dose-dependent trend. A gastroesophageal junction cancer patient who failed 3 prior lines of systemic therapy achieved a confirmed partial response and a PFS of 126 days. Another 2 patients achieved stable disease. A non-small cell lung cancer patient who failed 3 prior lines of systemic therapy achieved a PFS of 88 days, and an esophageal squamous cell carcinoma patient who failed 3 prior lines of systemic therapy has been followed up for 112 days to date and has not experienced disease progression.“As a novel personalized mRNA cancer vaccine, EVM16 has demonstrated encouraging clinical development potential in its first-in-human clinical trial,” said Professor Shen Lin, Director of the Gastrointestinal Oncology Department at Beijing Cancer Hospital and Chair of the Gastric Cancer Expert Committee of the Chinese Society of Clinical Oncology. “The data show a favorable safety and tolerability profile in patients with advanced solid tumors, with no dose-limiting toxicities (DLTs) observed. Importantly, EVM16 stimulated neoantigen-specific T cell responses with a dose-dependent trend, highlighting its consistent immune activation capability. Preliminary anti-tumor activity signals, including partial response (PR) and stable disease (SD), were observed in patients who had failed multiple lines of standard-of-care therapies, suggesting potential clinical activity. These findings provide early clinical validation of EVM16 and reinforce its differentiated mechanism as a personalized mRNA cancer vaccine. While immunotherapies, including checkpoint inhibitors, have transformed the treatment landscape in selected tumor types, most patients, particularly those with heavily pretreated advanced solid tumors, still represent a significant unmet medical need. Personalized mRNA cancer vaccines represented by EVM16 may help expand the population benefiting from immunotherapy and provide additional treatment options.” “The favorable safety, tolerability, immunogenicity, and preliminary efficacy results for EVM16 provide initial evidence of its therapeutic potential and support the clinical value of our in-house mRNA platform,” said Mr. Rogers Yongqing Luo, Chief Executive Officer of Everest Medicines. “Patients with advanced solid tumors, particularly those who have failed multiple lines of therapy, continue to suffer from limited treatment options. As our first in-house developed personalized mRNA cancer vaccine, EVM16 demonstrates the ability to induce immune activation and generate neoantigen-specific T cell responses, which may help reduce the risk of tumor metastasis or recurrence. This further underscores its potential as a novel approach in cancer immunotherapy. This project is powered by EVER-NEO-1, Everest’s proprietary AI-based neoantigen prediction algorithm. It analyzes patient-specific tumor mutations to identify highly immunogenic neoantigens and support the design of personalized mRNA vaccine candidates. The algorithm incorporates iterative learning capabilities designed to continuously improve neoantigen prediction accuracy and selection efficiency. Leveraging our leading mRNA platform, we will continue to advance the clinical development of EVM16 and bring this innovative therapy to more patients.”Everest Medicines has localized its clinically validated proprietary AI+mRNA platform, establishing an end-to-end integrated platform spanning antigen design, mRNA sequence optimization, lipid nanoparticles (LNP) targeted delivery and scalable manufacturing, with the potential to address significant unmet medical needs globally.EVM16 is a novel personalized therapeutic mRNA cancer vaccine in-house developed by Everest. It contains neoantigens with high immunogenicity potential, predicted based on the unique tumor mutations of each patient using Everest’s proprietary AI-based neoantigen prediction algorithm, EVER-NEO-1. The vaccine is designed to encode dozens of tumor neoantigens. The vaccine uses a lipid nanoparticle (LNP) delivery system to efficiently deliver neoantigen-encoded mRNA in vivo, activating neoantigen-specific tumor-killing T cells and inhibiting tumor growth.From an investment and market perspective, personalized cancer vaccines are in an early stage of breakthrough. According to Grand View Research, the global personalized cancer vaccine market is projected to reach $1.45 billion by 2030, with a staggering compound annual growth rate (CAGR) of 44.86% from 2025 to 2030. Myguide Securities points out that mRNA cancer vaccines have the potential to achieve pan-cancer coverage while offering the advantages of high accessibility, “off-the-shelf” availability, and personalization. As a highly promising new form of immunotherapy, it can enter clinical use as adjuvant therapies through extensive combinations, gradually unlocking a market space worth tens of billions of dollars.Against this backdrop, Everest Medicines is accelerating its strategic positioning in this field, progressively building a research and development pipeline with global competitiveness. Leveraging its proprietary AI+mRNA platform and its leading clinical position in China, Everest Medicines is currently at a critical juncture for industrialization and valuation growth. The upcoming readout of first-in-human (FIH) clinical trial data for EVM16 is expected to further release clinical and commercial potential, continuing to attract focus from the market and investors, and helping the company achieve a significant leap in value within the immunotherapy sector. Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

HONG KONG, Apr 21, 2026 - (ACN Newswire via SeaPRwire.com) - Seven annual lifestyle and licensing mega events organised by the Hong Kong Trade Development Council (HKTDC) are set to open next week. These include the Hong Kong Gifts & Premium Fair, Home InStyle and Fashion InStyle on 27-30 April at the Hong Kong Convention and Exhibition Centre, HKCEC; and the Hong Kong International Printing & Packaging Fair and DeLuxe PrintPack Hong Kong co-organised by the HKTDC and CIEC Exhibition Company (HK) Limited, held concurrently at AsiaWorld-Expo on 27-30 April; and the Hong Kong International Licensing Show and Asian Licensing Conference on 27-29 April at the HKCEC.Global exhibitors will showcase offerings spanning gifts and premiums, stylish houseware, trendy fashion, innovative materials for garment and homeware, gerontechnology, cultural and creative design products, sustainable products, green printing and packaging and intellectual property. The events fully leverage Hong Kong's unique connectivity between Chinese Mainland and international markets, reinforcing the city's position as a regional creative hub and international business centre, and actively aligning with the national 15th Five-Year Plan and dual circulation development strategy.HKTDC Deputy Executive Director Jenny Koo said: "The HKTDC has long facilitated trade exchanges across industries through organising a wide range of conferences and exhibitions, fulfilling Hong Kong's roles as a super connector and super value-adder while showcasing its strengths in new quality productive forces, product quality and creativity. This year, the seven mega lifestyle and licensing exhibitions and conference are being held concurrently during the final week of April. Buyers can enjoy a one-stop sourcing experience across all fairs, fostering cross-industry and cross-sectoral exchanges, generating greater synergies, and helping expand customer bases and business opportunities."The seven mega exhibitions and conference are expected to attract some 5,600 exhibitors from more than 30 countries and regions, including Hong Kong, Chinese Mainland, Asia, Europe and the Middle East. First-time exhibitors this year include participants from Finland, Germany, Iceland, the United Arab Emirates and Uzbekistan.Home InStyle welcomes new pavilions from Xinjiang and Wuhan; The Gifts & Premium Fair features new pavilions from Shanxi, Jilin, Huangnan Tibetan Autonomous Prefecture and Zhejiang, with the Zhejiang pavilion, organised for the first time by the Zhejiang Provincial Department of Commerce, bringing together 50 local enterprises. The Printing & Packaging Fair includes a new Fujian Quanzhou pavilion and Fashion InStyle features new pavilions from Jiangsu Sheyang, India and Indonesia, offering buyers an even more diverse range of sourcing options.The HKTDC continues to encourage the industry to embrace sustainable development and promote the use of innovative materials. This year, the seven fairs will collectively bring together over 820 green exhibitors. In addition, approximately 80 exhibitors will showcase innovative material products spanning houseware, home textiles, fashion, printing and packaging, and other sectors.Reimagine themed floor converges gifts and homeware creative inspirationIn keeping with market developments, HKCEC Hall 5 has transformed into aReimagine themed floor this year. The Reimagine floor presents a new vision of future lifestyles by seamlessly connecting the innovative, design and cultural creative elements of both the Gifts & Premium Fair and Home InStyle. This enables buyers to gain a one-stop overview of the latest global lifestyle homeware and gifting trends, while inspiring industry players to reimagine the boundless possibilities of future products and creative inspiration. The floor has several highlighted zones, including the Gifts & Premium Fair's new Selection of ASEAN and The Bespoke Hub and the Hong Kong Smart Design Global Awards, Home InStyle's Cultural and Creative Avenue and Gerontech and Innovative Material Pavilion.The Hong Kong Smart Design Global Awards, organised by the Hong Kong Exporters’ Association and sponsored by the Cultural and Creative Industries Development Agency (CCIDA), is renamed this year in recognition of Hong Kong's original design talent. The grand finale will be held during the Gifts & Premium Fair, with all finalist entries displayed on-site, giving exhibitors direct access to international buyers to enhance brand visibility and expand collaboration opportunities.The Cultural and Creative Avenue brings together over 110 exhibitors from over 10 countries and regions, presenting distinctive brands and designs that celebrate diverse cultural heritages. The zone once again partners with Pantone, using the PANTONE 2026 Colour of the Year "Cloud Dancer" as its theme to curate home décor settings, helping buyers understand how colour coordination can be harnessed to create stylish living spaces.Innovative materials debut at Home InStyleGlobal ageing is driving sustained growth in silver market demand, with the industry actively developing gerontechnology living products and solutions incorporating smart technologies to support home fitness, rehabilitation and daily living needs. Meanwhile, the development and application of innovative materials have also become a focal point in the homeware market. In response to these trends, Home InStyle will showcase innovative materials applied to the homeware and home textiles market for the first time this year. Building on the success of last year's gerontech living product showcase, both elements have been brought together in the Gerontech and Innovative Material Pavilion, funded by the Innovation and Technology Commission, with over 20 local exhibitors joining to inject fresh innovation into the homeware market.A series of events will also be held during the fairs, covering the silver economy, market trends, culture and innovation, and sustainability, helping the industry stay abreast of the latest market developments. Among them, the HKTDC, will co-organise a thematic seminar with the Federation of Hong Kong Industries (FHKI) and the Hong Kong Q-Mark Council, inviting representatives from the FHKI, the Hong Kong Council of Social Service and technology experts, to explore how to respond to the silver market through the introduction of the "Silver Q Mark" and certified gerontech living products. On sustainability, the Business Environment Council and representatives from eco-conscious enterprises will also analyse trends and breakthroughs in sustainable home and gift design.Fashion InStyle reveals how diverse materials collide to drive fashion innovationFashion InStyle features multiple exhibition zones, including Designer Spotlight, Materials Bazaar, Fashion Accessories, Women in Style, Bridal & Evening Wear, and Athleisure, etc. Among them, NEXT@Fashion InStyle (NEXT), the highlighted zone organised by HKTDC and sponsored by the Cultural and Creative Industries Development Agency (CCIDA) of the Hong Kong SAR Government, returns in full force this year, demonstrating how materials innovation in fashion can drive industry transformation and advance sustainability.This year, the Philippines is NEXT's featured partner, powered by The Philippine Trade and Investment Centre – Hong Kong (PTIC-HK) and the Center for International Trade Expositions and Missions (CITEM), more than 25 Philippine exhibitors showcasing the unique strengths of their local fashion materials. NEXT has also brought together over 60 global exhibitors from an ever-wider geographical reach, spanning not only Hong Kong, Chinese Mainland and the Philippines, but also other Asian markets such as Indonesia and Thailand. This year, several Nordic countries join the showcase, including Iceland, Finland and Sweden, further elevating NEXT's international profile and cementing its role as a global exchange platform for leading future fashion trends.NEXT has once again invited Han Chong, founder and creative director of contemporary fashion brand Self-Portrait, to serve as the project ambassador. Chong will lead six local designer brands in selecting forward-looking materials from eight suppliers to develop five cross-disciplinary design projects. This year marks the first time that materials sourced from outside Hong Kong are incorporated into the designs. The collections explore three overarching themes namely cultural & heritage, sustainability, and technology and functionality. All completed designs will be unveiled at the NEXT Fashion Parade on the second evening of the Fair (28 April).Two PrintPack Fairs present latest trends of smart technology and green packagingThis year's Printing & Packaging Fair introduces new products and solutions in smart packaging and innovative materials, with a spotlight on advanced RFID and anti-counterfeiting packaging technologies. Some exhibitors will also present packaging products made from plant-based or bio-based materials. The popular Green Printing & Packaging Solutions Zone returns once again, facilitating buyers identify packaging options that are more eco-friendly, efficient and practical.DeLuxe PrintPack Hong Kong focuses on premium printing and packaging solutions for high-end goods including jewellery, watches, cosmetics and fine wine. Many exhibitors will showcase distinctive packaging designs for six-star hotels and luxury brands, highlighting exceptional craftsmanship and refined brand aesthetics. The two fairs will also feature a series of seminars covering AI, sustainability and creative design. Representatives from FUJIFILM and BW Design Centre will share insights into the application of AI in printing and design. On the sustainability front, seminars will explore on new materials, smart technologies and innovative design in packaging, examining how the industry can enhance sustainability through the adoption of advanced materials. On creative design, renowned designers will discuss how design excellence, strong brand imagery and innovative elements can elevate product appeal and reinforce brand distinction.Hong Kong International Licensing Show and Asian Licensing Conference connect global opportunities Now in its 23rd edition, the Hong Kong International Licensing Show, Asia's flagship licensing event, brings together over 600 brands and intellectual properties (IPs) from multiple countries and regions, including Bandai Namco, Doraemon and LINE FRIENDS, spanning licensing categories such as arts and culture, animation and characters, brand extension, entertainment, lifestyle and sports. The event serves as a cross-regional and cross-sectoral business expansion platform for global licensors, brands and IP owners worldwide.The Design Licensing and Business (DLAB) Support Scheme, organised by the Innovative Entrepreneur Association (IEA) and sponsored by the CCIDA of the HKSAR Government, will once again participate in the Licensing Show. The dedicated DLAB Hong Kong Pavilion will showcase close to 40 local IPs and brands. Some IPs, including Animomo and Emo Neko Club, tap into the increasingly popular "emotional economy" concept, forging deeper emotional connections with consumers through emotional value, nostalgic elements and heartwarming stories. The Hong Kong Licensing Force Showcase also returns, collaborating with Hang Seng University of Hong Kong, Hong Kong Baptist University, Hong Kong Design Institute and The Hong Kong Polytechnic University to showcase innovative licensing concepts and design prowess of the next generation of creative talent.As e-commerce economy continues to flourish and IP market sales models continue to evolve, the show introduces for the first time a dedicated "IP and e-Commerce Support Services" Zone. Aligned with the HKSAR Government’s policy direction to actively enhance Hong Kong companies’ competitiveness on cross-border e-commerce platforms, it brings together e-commerce platforms, KOLs, marketing and PR firms to help brands and IPs expand into e-commerce markets and capitalise on online business opportunities.The concurrent Asian Licensing Conference, under the theme "Connecting Creativity, Unlocking Licensing Power", brings together industry leaders to explore the latest developments and opportunities in the global licensing market. Key topics this year include "Global Licensing Trends to Watch in 2026", "Perfectly Imperfect: The Rise of Fugglers in the Emotional Economy", Winning Off the Field: The Business Strategy behind Successful Sports Licensing", "The LBE Revolution: Engaging Audiences Beyond the Screen" and "VTubers: Redefining Entertainment in the Digital Age", offering the industry forward-looking insights and analysis.EXHIBITION+ Integrates online and offline experiences; AI boosts sourcing efficiencyThe seven exhibitions and conference continue to adopt the EXHIBITION+ hybrid format. In addition to the physical fairs, the “Click2Match” will leverage AI to provide business matching for exhibitors and buyers. Buyers can also use “Scan2Match” to scan exhibitors' QR codes, bookmark exhibitors and continue discussions online during or after the fairs. The fairs will also introduce an AI-driven SmartBot service on-site for the first time, enabling buyers to search more swiftly for products and exhibitors and instantly generate personalized visit routes.Photo Download: http://bit.ly/3OSQRvFIntroducing highlights of the seven lifestyle and creative events at today’s press conference were (from left to right) Katherine Fang, Chairman of the HKTDC Garment Advisory Committee; Jeffrey Lam, Chairman of the HKTDC Home InStyle and Hong Kong Gifts & Premium Fair Organising Committee; Jenny Koo, Deputy Executive Director of the HKTDC; Helena Chiu, Chairman of the Hong Kong Exporters' Association; and Zacharias Cheng, President of the Innovative Entrepreneur Association (IEA)Hong Kong Gifts & Premium Fair exhibitor Wei Yit Vacuum Flask Manufactory Ltd unveils its new Series 116 vacuum flask blind box, designed by Hong Kong illustrator Pen So and Hong Kong contemporary artist Jerry Cho. Each piece features intricately illustrated Hong Kong streetscapes, making it highly collectibleHome InStyle exhibitor features a smart fitness training system at the Gerontech and Innovative Material Pavilion. Powered by AI and data-driven training, the system collects and analyses user data to formulate personalised exercise plans, enabling seniors to build strength at homeNEXT@Fashion InStyle features designs that offer contemporary reinterpretations of cultural heritage. Design studio Tigerstrolling fuses Song Brocade, a national-level intangible cultural heritage, with denim, while weaving in Hong Kong cultural elements to breathe fresh street energy into the intangible cultural heritage traditionHong Kong International Printing & Packaging Fair exhibitor introduces eco-friendly wet-pressed pulp moulded packaging boxes made primarily from wood pulp and sugarcane pulp. Biodegradable and fully recyclable, the boxes also offer moisture-proof, waterproof, oil-resistant and dust-resistant propertiesDeLuxe PrintPack Hong Kong exhibitor showcases packaging boxes made of carbon fibre. Previously used in automotive and sports equipment, the material is now being applied to lifestyle products for its lightweight and impact-resistant propertiesHong Kong International Licensing Show exhibitor presents their pixel-art IP character Potatoz and a series of products inspired by the IPEvents Details:EventsEvent DateOpening HoursVenueHong Kong Gifts & Premium Fair 27–29 Apr(Mon–Wed)30 Apr(Thu) 9:30am – 6:30pm9:30am – 5:00pm HKCECHome InStyleFashion InStyleHong Kong International Printing & Packaging Fair27 Apr(Mon)28–29 Apr(Tue–Wed)30 Apr(Thu)10:30am –5:30pm 9:30am – 5:30pm9:30am – 3:30pm AsiaWorld-ExpoDeLuxe PrintPack Hong KongHong Kong International Licensing Show27–28 Apr(Mon–Tue) 29 Apr(Wed) 9:30am – 6:30pm 9:30am – 5:00pm HKCECAsian Licensing ConferenceMedia enquiriesFor enquiries, please contact:Home InStyle, Fashion InStyle, HK Gifts & Premium Fair, HK International Printing & Packaging Fair and DeLuxe PrintPack Hong KongPandagon:Fraser LiTel: 6083 5623Email: pandagon.limited@gmail.comHKTDC’s Communications & Public Affairs Department:Clayton LauwTel: 2584 4472Email: clayton.y.lauw@hktdc.org HK International Licensing Show and Asian Licensing ConferenceRaconteur: Molisa LauTel: 6187 7786Email: molisalau@raconteur.hkBetsy TseTel: 9742 7338Email: betsytse@raconteur.hk HKTDC’s Communications & Public Affairs Department:Winnie KanTel: 2584 4055Email: winnie.wy.kan@hktdc.orgHKTDC Newsroom: http://mediaroom.hktdc.com/enAbout HKTDCThe Hong Kong Trade Development Council (HKTDC) celebrates its 60th anniversary this year. The HKTDC is a statutory body established in 1966 to promote, assist and develop Hong Kong's trade. With over 50 offices globally, including 13 in the Chinese Mainland, the HKTDC promotes Hong Kong as a two-way global investment and business hub. The HKTDC organises international exhibitions, conferences and business missions to create business opportunities for companies, particularly small and medium-sized enterprises (SMEs), in the mainland and international markets. The HKTDC also provides up-to-date market insights and product information via research reports and digital news channels. For more information, please visit: www.hktdc.com/aboutus. Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

SUNNYVALE, CA, Apr 22, 2026 - (ACN Newswire via SeaPRwire.com) - Graid Technology, the pioneer in GPU-accelerated NVMe storage, today announced its Agentic AI Storage Portfolio: a purpose-built family of KV cache solutions designed to eliminate the storage bottleneck that stalls "always-on" production AI. The portfolio spans three deployment tiers: KV Cache Server, KV Cache Rack, and KV Cache Platform, all built on SupremeRAID™ technology. KV Cache Platform, the portfolio's highest tier, is purpose-aligned to NVIDIA's STX reference architecture, with native BlueField-4 DPU execution on the roadmap for H2 2026.As agentic AI moves from experimentation to production, the infrastructure assumptions that underpinned single-shot inference have broken down. Models running continuous multi-step tasks and maintaining context across hours of operation generate KV cache demands that overwhelm GPU HBM. The result: latency spikes up to 18x, GPU utilization as low as 50%, and model-level failures, including hallucinations and reasoning degradation, that are difficult to detect and costly to recover from.SupremeRAID™ addresses this directly, aggregating up to 32 NVMe drives into a single 280 GB/s virtual pool, bypassing the CPU via GPU Direct Storage, and delivering KV cache reads at 1.3ms- 77x faster than standard NVMe. The three portfolio tiers bring this capability to every deployment scale:KV Cache Server - single-node NVMe acceleration for individual inference servers and edge AI deployments. Available now.KV Cache Rack - rack-scale, partner-validated solutions co-engineered with leading server OEM partners for enterprise multi-GPU clusters. Available now.KV Cache Platform - Purpose-built for NVIDIA's STX reference architecture, with native BlueField-4 DPU execution and rack-scale storage expansion on the roadmap."A year ago, at GTC 2025, Jensen Huang predicted that storage would become GPU-accelerated for the first time. This year, NVIDIA turned that concept into an architecture with STX and CMX," said Leander Yu, CEO of Graid Technology. "Our KV Cache Portfolio is built for precisely this moment, delivering the storage performance that agentic AI demands, at storage-tier economics."For enterprises and infrastructure teams evaluating agentic AI deployments, the full deployment architecture, technical specifications, and NVIDIA STX compatibility details are available in the solution brief: Graid Technology Agentic AI Storage Portfolio: Purpose-built KV Cache Solutions for Inference at Scale.To learn more about Graid Technology's AI offerings, visit graidtech.com/ai.Media Inquiries:Andrea Eaken, Sr. Director of Marketing, Americas & EMEAandrea.eaken@graidtech.comAbout Graid TechnologyGraid Technology is building the storage backbone for the future of AI, enterprise, and high-performance computing. As the creator of SupremeRAID™, the world's first and only GPU-based RAID, and the global steward of Intel® Virtual RAID on CPU (Intel® VROC), Graid Technology delivers flexible RAID solutions that maximize NVMe performance while ensuring resilient, scalable data protection for modern data infrastructure. Headquartered in Silicon Valley with global operations and R&D in Taiwan, Graid Technology is advancing RAID innovation for the next generation of data-intensive workloads. To learn more, visit graidtech.com.SOURCE: Graid Technology Inc. Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

TSUKUBA, Japan, Apr 22, 2026 - (ACN Newswire via SeaPRwire.com) - Discovering and characterizing new materials is important for unlocking advances in fields like clean energy, advanced manufacturing, and improved infrastructure. Researchers use machine learning and other computational tools to help them, but the trial-and-error nature of the process creates specific challenges. The research produces large amounts of experimental and computational data, and scientists need tools that can track and store not only the results but also the chain of reasoning behind them.A newly developed system tracks and stores not only the results but also the chain of reasoning behind them, allowing researchers to review the decision making process for a greater transparency and reproducibility in materials science research.A new system called pinax, published in the journal Science and Technology of Advanced Materials: Methods, provides precisely those features. Developed by engineers at Japan’s National Institute for Materials Science (NIMS), pinax captures the entire process of developing new materials, including machine learning workflows and decision-making processes. “By formalizing both successful and unsuccessful trial-and-error processes, pinax enhances reproducibility, accountability, and knowledge sharing while maintaining strict data governance,” says Satoshi Minamoto of NIMS, the study’s lead author.The new pinax system consists of three layers: the core machine learning infrastructure (bottom), the provenance recording and tracking that visualises the reasoning behind final results (middle), and the advanced feature layer for materials development (top). Credit: STAM-MMachine learning models are playing an ever-larger role in materials discovery and characterization. While the models are powerful tools, the reasoning processes they use are generally opaque. Researchers don’t know what considerations and trial-and-error processes went into their final predictions. “The system introduced in this study visualizes these invisible processes. This enables others to review, verify, and build upon the path to the conclusions,” says Minamoto.Minamoto highlights the importance of such access in applications where safety, reproducibility, and accountability are important, saying that this work “demonstrates how transparent AI systems can transform scientific discovery into a more reliable, efficient, and socially responsible endeavor.”The team tested pinax using two case studies: one on predicting steel properties and another using transfer learning to predict the thermal conductivity of polymers. The system made it possible to link the model’s performance predictions to the specific data or model aspects that influenced them, and to reproduce complex, multi-stage workflows. “In particular, the transfer-learning example highlights pinax’s ability to track how information flows between intertwined datasets and models, making every step in the reasoning process explicitly traceable,” says Minamoto.The engineers plan to expand pinax towards an autonomous, closed-loop materials discovery system. By integrating pinax’s tracking capabilities with automated experimental and simulation systems, they aim to create a loop that can use data generation, machine learning models, and decision-making systems to systematically and independently carry out the entire research cycle.Further information Satoshi MinamotoNational Institute for Materials Scienceminamoto.satoshi@nims.go.jpPaper: https://doi.org/10.1080/27660400.2026.2629051 About Science and Technology of Advanced Materials: Methods (STAM-M)STAM Methods is an open access sister journal of Science and Technology of Advanced Materials (STAM), and focuses on emergent methods and tools for improving and/or accelerating materials developments, such as methodology, apparatus, instrumentation, modeling, high-through put data collection, materials/process informatics, databases, and programming. https://www.tandfonline.com/STAM-MDr Kazuya SaitoSTAM Methods Publishing Director SAITO.Kazuya@nims.go.jpPress release distributed by Asia Research News for Science and Technology of Advanced Materials. Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com